Barring an unlikely return to the NBA somewhere down the line, the "All-Star" Kobe 11 will be the final Nike Kobe shoe that Kobe Bryant wears during an All-Star Game.
It's entirely possible that the Kobe line will continue after Bryant's retirement, and future shoes might even be included in Nike Basketball's All-Star efforts, but they won't actually be involved in the on-court festivities unless Nike finds someone else to take up the mantle.